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1.
Liquid Li metal is a promising nuclear reactor coolant; however, relevant research regarding its heat transfer characteristics remains insufficient. In this study, a steady-state two-dimensional mathematical model is established to describe the heat transfer process of liquid Li in a straight pipe. A numerical analysis is conducted to investigate the effects of inlet velocity, inlet temperature, and wall heat flux on heat transfer in liquid Li. The results indicate the advantage of using liquid Li for improving heat transfer at high inlet temperatures (> 1000 K) compared with using liquid sodium and lead–bismuth eutectic. Considering the mechanism of the outlet radial heat flow model, the ratio of turbulent to molecular diffusion coefficients presents a parabolic distribution along the radius of the pipe. Increasing the inlet velocity, decreasing the inlet temperature, and decreasing the wall heat flux can effectively weaken the dominant role of molecular heat transfer owing to the low Prandtl number of liquid Li. The heat transfer of liquid Li is investigated comprehensively in this study, and the results provide a basis for the practical application of liquid Li as a promising coolant.  相似文献   
2.
卡默勒的幻觉主义理论是现象意识分析中一种不同的声音。其幻觉主义理论认为:现象意识是一个幻觉;可基于相似性理论来解释现象意识的机制,指出现象意识就是外部物理性质经模块处理的结果,其处理过程遵循表象原则、接受喜好原则、配置原则和个例化原则;现象意识的幻觉元是解释现象意识为何强烈的问题。幻觉主义理论为现象意识的分析提供了一个新的思路,但也存在着如特殊心理模块等的理论缺陷。  相似文献   
3.
为了在保证较高水平的保障可用度前提下提高舰载机出动效率, 提出一种支持可用度约束的统计优化模型及其对应的启发式求解算法。能够同时生成舰载机的保障作业调度方案和保障装备计划性维护的时间安排, 并通过基于仿真的优化方式, 在启发算法的适应度评价中增加对视情维修和事后维修的仿真, 提高了舰载机作业调度方案的鲁棒性。仿真结果表明,所提算法能够提供一个稳定可靠的基准调度方案, 避免不必要的重调度。  相似文献   
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Extending visible light absorption range and suppressing the recombination of photogenerated charge carriers are always important topics in developing efficient solar-driven photocatalysts. In this study, the thermal treatment process at 400 °C in a high-pressure hydrogen atmosphere was applied to modify graphitic carbon nitride. Compared to the normal atmospheric hydrogen treatment process, this process has the merit of producing nitrogen deficient graphitic carbon nitride in high-yield. The optimal photocatalytic activity of modified graphitic carbon nitride was demonstrated by controlling the treatment duration in the hydrogen atmosphere.The changes in the crystal structure, microstructure and optical properties of carbon nitrides were investigated by several characterizations. The relationship between the photocatalytic activity and structures of graphitic carbon nitride was preliminarily established. The results obtained in this study could provide some new ways of improving the activity of graphitic carbon nitride based photocatalyst.  相似文献   
7.
The paper established a double filtering method (DFM) to visualize the skeleton industrial structure (SIS) of one economy and find its evolution rule. Different with the previous researches, this method is from a new view of industrial conjunctions combined by leading sectors to depict the industrial structure. It was proved that the leading sector selected by DFM must be key sector selected by Hirschman-Rasmussen method. Applied DFM to input-output tables of China, Japan and USA and MFA to Japan and USA, the results analysis showed that DFM could overtake the two main shortcomings of minimum flow analysis (MFA), scratch SIS of each economy with its own characteristics, visualize the general evolution rules of the industrial structure with crisscrossed conjunctions among leading sectors.  相似文献   
8.

Introduction

Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets and carried out in vitro islet hormone secretion studies to provide functional confirmation for the species-specific role of peptide YY (PYY) in mouse islets.

Materials and methods

GPCR peptide ligand mRNAs in human and mouse islets were quantified by quantitative real-time PCR relative to the reference genes ACTB, GAPDH, PPIA, TBP and TFRC. The pathways connecting GPCR peptide ligands with their receptors were identified by manual searches in the PubMed, IUPHAR and Ingenuity databases. Distribution of PYY protein in mouse and human islets was determined by immunohistochemistry. Insulin, glucagon and somatostatin secretion from islets was measured by radioimmunoassay.

Results

We have quantified GPCR peptide ligand mRNA expression in human and mouse islets and created specific signalomes mapping the pathways by which islet peptide ligands regulate human and mouse GPCR signalling. We also identified species-specific islet expression of several GPCR ligands. In particular, PYY mRNA levels were ~ 40,000-fold higher in mouse than human islets, suggesting a more important role of locally secreted Pyy in mouse islets. This was confirmed by IHC and functional experiments measuring insulin, glucagon and somatostatin secretion.

Discussion

The detailed human and mouse islet GPCR peptide ligand atlases will allow accurate translation of mouse islet functional studies for the identification of GPCR/peptide signalling pathways relevant for human physiology, which may lead to novel treatment modalities of diabetes and metabolic disease.
  相似文献   
9.
An innovative method for recovering valuable elements from vanadium-bearing titanomagnetite is proposed. This method involves two procedures: low-temperature roasting of vanadium-bearing titanomagnetite and water leaching of roasting slag. During the roasting process, the reduction of iron oxides to metallic iron, the sodium oxidation of vanadium oxides to water-soluble sodium vanadate, and the smelting separation of metallic iron and slag were accomplished simultaneously. Optimal roasting conditions for iron/slag separation were achieved with a mixture thickness of 42.5 mm, a roasting temperature of 1200°C, a residence time of 2 h, a molar ratio of C/O of 1.7, and a sodium carbonate addition of 70 wt%, as well as with the use of anthracite as a reductant. Under the optimal conditions, 93.67% iron from the raw ore was recovered in the form of iron nugget with 95.44% iron grade. After a water leaching process, 85.61% of the vanadium from the roasting slag was leached, confirming the sodium oxidation of most of the vanadium oxides to water-soluble sodium vanadate during the roasting process. The total recoveries of iron, vanadium, and titanium were 93.67%, 72.68%, and 99.72%, respectively.  相似文献   
10.
为计算具有随机不确定性和认知不确定性的混合不确定系统灵敏度,提出一种基于证据理论和条件概率理论的全局灵敏度分析方法.用证据理论对认知不确定性变量进行表征,并提出两种基于证据理论的随机采样方法,包括一次随机抽样法和二次随机抽样法.运用条件概率理论,提出存在认知不确定性条件下混合不确定系统的Sobol'全局灵敏度指标,经过理论推导给出一阶灵敏度及总灵敏度的计算公式,并设置单循环的拟蒙特卡罗方法实现灵敏度的近似数值计算.开发了灵敏度分析程序,并给出了典型应用实例.实例表明,新方法的分析结果正确,计算工作量可控.  相似文献   
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